Distinguished Scientist, Head of Investigative Toxicology US

Company: Sanofi
Location: Cambridge
Posted on: March 13, 2026

Job Description:

Job Title: Distinguished Scientist, Head of Investigative Toxicology US Location: Cambridge, MA About the Job Join the engine of Sanofis mission where deep immunoscience meets bold, AI-powered research. In R&D, youll drive breakthroughs that could turn the impossible into possible for millions. The incumbent will be responsible for oversight and management of the Investigative Toxicology laboratory in the US and execution of strategies to strengthen and evolve liver and immune-related safety assessment, incorporating microphysiological systems (MPS) where needed. This candidate will ensure that Sanofi employs an evolving, innovative strategy for assessing liver and immune-related risks that align with regulatory guidance and scientific practice. This role will involve direct supervision of laboratory colleagues and/or lab heads working transversally with colleagues within PCS and across Sanofi sites, and external vendors, to provide project support and drive collaboration. This role will also be responsible for leading efforts and devising strategies to manage safety issues relevant to molecules at all stages of the Research and Development portfolio, and providing subject matter expertise related to liver safety. Participation in external consortia and representing Sanofi at relevant scientific venues is also an important component of this role. Terms of employment Occasional domestic and international travel to Sanofi Research and Development sites (e.g Paris, France; Frankfurt, Germany) and scientific meetings. Availability to start in 1Q2026. What makes this position unique? The candidate will be part of an established highly effective Investigative Toxicology group at Sanofi and have opportunity to manage a laboratory and help shape and guide research in the toxicology field, particularly with respect to liver safety assessment and application of MPS models. There is also the opportunity to learn and grow in the immunotoxicology area. There is tremendous opportunity for innovation within the role, and the global scope will provide the candidate with a rich, diverse work experience. About Sanofi: Were an R&D-driven, AI-powered biopharma company committed to improving peoples lives and delivering compelling growth. Our deep understanding of the immune system and innovative pipeline enables us to invent medicines and vaccines that treat and protect millions of people around the world. Together, we chase the miracles of science to improve peoples lives. Main Responsibilities Supervise and manage colleagues in the US Investigative Toxicology group, including performance assessment and development planning; provide mentorship and guidance to support career growth. Provide technical expertise in model and assay development relevant for both liver and the immune system, ensuring sufficient scientific rigor. Oversee appropriate qualification/validation plans and testing strategies, particularly for the MPS models, to ensure robust performance. Define strategies and mechanistic experiments to understand safety issues; lead and manage execution of such strategies. Work collaboratively and transversally to ensure such strategies meet project and regulatory requirements; author reports to support inclusion of results in white papers or regulatory submissions as needed. Provide subject matter expertise on liver safety assessment and lead liver translational safety initiatives. Provide leadership regarding MPS models and in vitro new alternative models (NAMs) within Preclinical Safety and the broader Sanofi Research and Development organization. Participate in external consortia or working groups to stay abreast of liver safety knowledge and trends within the scientific community, regulatory environment, and the pharmaceutical industry. Represent Sanofi interests, maintaining high ethical and scientific standards. Author external presentations and manuscripts to contribute to scientific advancement of the toxicology field. About You Requirements & Qualifications A PhD in toxicology, pharmacology, biology, engineering, or equivalent scientific discipline required, with a minimum of 10 years of relevant experience in a pharmaceutical or biopharmaceutical setting. Knowledge and experience in liver toxicology and MPS models is required. Excellent management and leadership skills are essential. The ability to collaborate effectively with other scientists, subject matter experts and project teams is also essential. Experience working with immune models and immunotoxicology is a plus. Established record of scientific contribution in peer-reviewed journals and scientific symposiums. Excellent verbal and written communication skills are required. Why Choose Us? Bring the miracles of science to life alongside a supportive, future-focused team. Discover endless opportunities to grow your talent and drive your career, whether its through a promotion or lateral move, at home or internationally. Enjoy a thoughtful, well-crafted rewards package that recognizes your contribution and amplifies your impact. Take good care of yourself and your family, with a wide range of health and wellbeing benefits including high-quality healthcare, prevention and wellness programs and at least 14 weeks gender-neutral parental leave. Be part of an active, innovative scientific group Have diverse opportunities to collaborate on a global scale Be highly recognized for successes Receive excellent benefits and compensation Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law. GD-SA LI-SA LI-Onsite vhd All compensation will be determined commensurate with demonstrated experience. Employees may be eligible to participate in Company employee benefit programs, and additional benefits information can be found here.

Keywords: Sanofi, Concord , Distinguished Scientist, Head of Investigative Toxicology US, Science, Research & Development , Cambridge, New Hampshire