Head of Process Analytical Technology - Mammalian Platform
Company: Sanofi
Location: Framingham
Posted on: March 13, 2026
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Job Description:
Job Title: Head of Process Analytical Technology - Mammalian
Platform Location: Framingham, MA About Sanofi: Were an
R&D-driven, AI-powered biopharma company committed to improving
peoples lives and delivering compelling growth. Our deep
understanding of the immune system and innovative pipeline enables
us to invent medicines and vaccines that treat and protect millions
of people around the world. Together, we chase the miracles of
science to improve peoples lives. About the Job Join the engine of
Sanofis mission where deep immunoscience meets bold, AI-powered
research. In R&D, youll drive breakthroughs that could turn the
impossible into possible for millions. Are you ready to help create
the future of biomanufacturing? At Sanofi, we strive every day to
Take the Lead to innovate for patients with novel therapeutics and
manufacturing technology. Your leadership skills and expertise in
Process Analytical Technology (PAT) could be a key enabler that
helps us realize that future together. The Mammalian Platform (part
of Sanofi R&D) is responsible for the development, scale-up,
and transfer of upstream and downstream processes and their control
strategies for clinical and commercial manufacturing of therapeutic
proteins produced from mammalian cell lines. In addition, the
department actively invests in developing and implementing new
technologies related to integrated and continuous biomanufacturing,
process analytical technology (PAT), high throughput process
development, and modeling. Ultimately, our goal is to design robust
processes that produce safe and effective medicines as efficiently
as possible. We are looking for candidates to lead our Process
Analytical Technology activities across the Mammalian Platform
including applications for both cell culture and purification
processes. This individual should be able to combine innovation
leadership skills with technical expertise to continuously evolve
and lead teams in the delivery of our Process Analytical Technology
roadmap. The incumbent will lead in a matrixed structure,
leveraging resources across the platforms global footprint in both
the United States (Framingham, MA) and France (Vitry) while
representing the platform at the interface with our Commercial
Manufacturing and Supply (M&S) organization. This role will
report to the Global Head of Purification Development, providing a
direct link to Mammalian Platform leadership to support sustained
innovation and technology implementation in both clinical and
commercial manufacturing applications. Main Responsibilities: Lead
the development and implementation of Process Analytical Technology
for the Mammalian Platform, including cell culture and purification
applications Drive the design and evolution of our Process
Analytical Technology roadmap to enable near-term implementation
and long-term disruptive innovation Represent the Mammalian
Platform for PAT-related topics, interfacing with Commercial
Manufacturing and Quality, as well as other Platforms within
R&D (Microbial, Genomic Medicines, mRNA, Vaccines, Synthetics)
Engage relevant stakeholders across R&D and Commercial
Manufacturing to ensure resources, budget, and implementation risk
are adequately managed and communicated Identify opportunities to
improve our process development strategies and manufacturing
approaches through the application of PAT Act as a PAT champion
across the Sanofi R&D and Manufacturing network Mentor
scientists across sites and teams fostering their career
development and professional growth About You Basic Qualifications:
PhD. in Biochemical Engineering, Chemical Engineering, Analytical
Chemistry, Physics, Bioengineering, Electrical Engineering, or
related fields with at least 7 years of experience or a M.S. with
at least 11 years of relevant experience or a B.S. with at least 12
years of relevant experience Relevant industrial experience and/or
academic experience in Process Analytical Technology development
Preferred Qualifications: Experience with spectroscopic Process
Analytical Technology (Raman, Near-Infrared, Mid-Infrared,
Fluorescence, UV-Vis) techniques Experience with online or inline
analyzers for Process Analytical Technology applications (HPLC,
UPLC, LCMS, DLS, MALS) and auto-sampling techniques Understanding
of PAT-enabling digital architecture and its application in
manufacturing settings (SynTQ, SIMCA-Online, Distributed Control
Systems) Familiarity with relevant Regulatory and Quality
frameworks related to control strategy, method qualification,
process validation, and data integrity Understanding of upstream
and downstream unit operations, process development, and technology
transfer Understanding of product quality attributes of therapeutic
proteins (antibodies, multi-specific antibodies, fusion proteins,
enzymes) Ability to lead a diverse, cross-functional, cross-site
matrixed team Excellent communication skills in both written and
oral settings High level of scientific curiosity and innovation
mindset Why Choose Us? Bring the miracles of science to life
alongside a supportive, future-focused team. Discover endless
opportunities to grow your talent and drive your career, whether
its through a promotion or lateral move, at home or
internationally. Enjoy a thoughtful, well-crafted rewards package
that recognizes your contribution and amplifies your impact. Take
good care of yourself and your family, with a wide range of health
and wellbeing benefits including high-quality healthcare,
prevention and wellness programs and at least 14 weeks
gender-neutral parental leave. Sanofi Inc. and its U.S. affiliates
are Equal Opportunity and Affirmative Action employers committed to
a culturally diverse workforce. All qualified applicants will
receive consideration for employment without regard to race; color;
creed; religion; national origin; age; ancestry; nationality;
marital, domestic partnership or civil union status; sex, gender,
gender identity or expression; affectional or sexual orientation;
disability; veteran or military status or liability for military
status; domestic violence victim status; atypical cellular or blood
trait; genetic information (including the refusal to submit to
genetic testing) or any other characteristic protected by law.
GD-SA LI-SA LI-Onsite vhd All compensation will be determined
commensurate with demonstrated experience. Employees may be
eligible to participate in Company employee benefit programs, and
additional benefits information can be found here.
Keywords: Sanofi, Concord , Head of Process Analytical Technology - Mammalian Platform, Science, Research & Development , Framingham, New Hampshire
